| 1 | Jamie Jurak (Senior) | USA | 1:19.65 | PB | - |
| 2 | Greta Myers (B2) | USA | 1:20.69 | | +1.040 |
| 3 | Blair Cruikshank (Neo) | USA | 1:21.30 | SB | +1.650 |
| 4 | Dessie Weigel (Senior) | USA | 1:22.39 | | +2.740 |
| 5 | Chrysta Rands (Senior) | USA | 1:22.45 | SB | +2.800 |
| 6 | Laura Michelle Rodriguez (C2) | COL | 1:22.57 | NRJ | +2.920 |
| 7 | Ilsa Melin Sandvig Shobe (Neo) | USA | 1:24.46 | | +4.810 |
| 8 | Ranja Ezzi (M35) | SWE | 1:24.74 | NRM | +5.090 |
| 9 | Maria Victoria Rodriguez (Senior) | ARG | 1:25.26 | | +5.610 |
| 10 | Natalia Valencia (Neo) | COL | 1:26.16 | | +6.510 |
| 11 | Larissa Paes (Senior) | BRA | 1:26.95 | | +7.300 |
| 12 | Thalia Staehle (B2) | USA | 1:26.95 | | +7.300 |
| 13 | Cynthia Jennings (Senior) | USA | 1:27.48 | SB | +7.830 |
| 14 | Shruti Kotwal (Senior) | IND | 1:27.57 | NR | +7.920 |
| 15 | Isabela Vargas Rodriguez (C1) | COL | 1:28.33 | | +8.680 |
| 16 | Mariana Caro (n/a) | COL | 1:35.22 | PB | +15.570 |
| 17 | Avery Hayes (D1) | USA | 1:49.74 | | +30.090 |
| 18 | Rz Love (D1) | USA | 1:57.15 | | +37.500 |
| 19 | Sky Thatcher (n/a) | USA | 2:05.03 | SB | +45.380 |
| DNS | Jenni Kukkonen (Senior) | FIN | DNS | | - |
| DQ | Ella Teeples (D1) | USA | DQ | | - |